Validation of the Cellbox® for Simulated Transport of a Liver derived Cancer Cell Line

12.02.2020 - Birte Steinbach



Key Words
HepG2, Portable CO2 incubator, Live Cell Shipper, Cell Viability, Transport, Shipping.

Goals
To validate the performance of the Cellbox® flight CDI as a CO2 incubator for cultivating cells under stationary and simulated transport conditions.

Abstract
The quality and viability of biological cells and tissues can be severely impacted by inadequate shipping conditions. To address this issue, Cellbox Solutions GmbH has developed a live cell shipper for transporting cells under laboratory conditions. In this application note the performance of the Cellbox® flight CDI was investigated by comparing it to a standard CO2 incubator. Experiments performed at the Fraunhofer IME ScreeningPort assessed the ability of the Cellboxâ to maintain cultures of HepG2 cells under stationary and simulated transport conditions. Assays testing the viability, confluency and mitochondrial morphology of HepG2 cells confirmed that the Cellbox® provides incubation conditions that are equivalent to a standard CO2 incubator during stationary and simulated transport conditions.


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